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1

Navigating the Island of Reil: how to understand the insular cortex

Wynford-Thomas, Ray, Powell, Rob

Journal:

Practical Neurology

Year:

2017

Language:

english

File:

PDF, 2.97 MB

english, 2017

2

Spontaneous de-differentiation correlates with extended lifespan in transformed thyroid epithelial cells: An epigenetic mechanism of tumour progression?

Jane A. Bond, Gro Oddweig Ness, Janet Rowson, Mircea Ivan, Denise White, David Wynford-Thomas

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 918 KB

english, 1996

3

Evidence against involvement of APC mutation in papillary thyroid carcinoma

Curtis, L., Wyllie, A.H., Shaw, J.J., Williams, G.T., Radulescu, A., DeMicco, C., Haugen, D.R.F., Varhaug, J.E., Lillehaug, J.R., Wynford-Thomas, D.

Journal:

European Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 828 KB

english, 1994

4

A CHALLENGING CASE: SPINAL CORD SARCOIDOSIS

Wynford-Thomas, R., Smith, P.

Journal:

Journal of Neurology Neurosurgery & Psychiatry

Year:

2014

Language:

english

File:

PDF, 42 KB

english, 2014

5

10.1038/7827

Kipling, David, Wynford-Thomas, David, Jones, Chris J., Akbar, Arne, Aspinall, Richard, Bacchetti, Silvia, Blasco, Maria A., Broccoli, Dominique, DePinho, Ron A., Edwards, Dylan R., Effros, Rita B., H

Journal:

Nature Biotechnology

Year:

1999

Language:

english

File:

PDF, 88 KB

english, 1999

6

Control of Replicative Life Span in Human Cells: Barriers to Clonal Expansion Intermediate Between M1 Senescence and M2 Crisis

Bond, J. A., Haughton, M. F., Rowson, J. M., Smith, P. J., Gire, V., Wynford-Thomas, D., Wyllie, F. S.

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 2.41 MB

english, 1999

7

Neurological update: MOG antibody disease

Wynford-Thomas, Ray, Jacob, Anu, Tomassini, Valentina

Journal:

Journal of Neurology

Year:

2018

Language:

english

File:

PDF, 1.48 MB

english, 2018

8

IN VIVO PHOTOINDUCTION OF METALLOTHIONEIN IN HUMAN SKIN BY ULTRAVIOLET IRRADIATION

ANSTEY, ALEXANDER, MARKS, RONALD, LONG, COLIN, NAVABI, HOSSEIN, PEARSE, ANTHONY, WYNFORD-THOMAS, DAVID, JASANI, BHARAT

Journal:

The Journal of Pathology

Year:

1996

Language:

english

File:

PDF, 573 KB

english, 1996

9

REVIEW ARTICLE. p53: GUARDIAN OF CELLULAR SENESCENCE

WYNFORD-THOMAS, DAVID

Journal:

The Journal of Pathology

Year:

1996

Language:

english

File:

PDF, 369 KB

english, 1996

10

Sporadicret-rearranged papillary carcinoma of the thyroid: a subset of slow growing, less aggressive thyroid neoplasms?

Soares, Paula, Fonseca, Elsa, Wynford-Thomas, David, Sobrinho-Simões, Manuel

Journal:

The Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 267 KB

english, 1998

11

Cellular senescence and cancer

Wynford-Thomas, David

Journal:

The Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 280 KB

english, 1999

12

Loss of responsiveness to transforming growth factor β (TGFβ) is tightly linked to tumorigenicity in a model of thyroid tumour progression

Jeremy P. Blaydes, David Wynford-Thomas

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 828 KB

english, 1996

13

Cytotoxic action of phorbol esters on human pancreatic cancer cells

Jane A. Bond, Andreas J. Gescher, Richard D. Verschoyle, Nicholas R. Lemoine, Rachel Errington, Marie Wiltshire, Paul J. Smith, David Wynford-Thomas

Journal:

International Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 1.38 MB

english, 2007

14

Suppression of transformation and immortality in human/chinese hamster fibroblast hybrids—a model for suppressor gene isolation

D. Wynford-Thomas, J. A. Bond, H. Paterson

Journal:

International Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 1.51 MB

english, 1989

15

Abnormalities of the EGF receptor system in human thyroid neoplasia

Nicholas R. Lemoine, Christine M. Hughes, William J. Gullick, Christopher L. Brown, David Wynford-Thomas

Journal:

International Journal of Cancer

Year:

1991

Language:

english

File:

PDF, 512 KB

english, 1991

16

Effect of serum growth factors and phorbol ester on growth and survival of human thyroid epithelial cells expressing mutant ras

Jane Bond, Tim Dawson, Nick Lemoine, David Wynford-Thomas

Journal:

Molecular Carcinogenesis

Year:

1992

Language:

english

File:

PDF, 776 KB

english, 1992

17

Stepwise transformation of primary thyroid epithelial cells by a mutant Ha-ras oncogene: An in vitro model of tumor progression

Jorge S. Burns, Jeremy P. Blaydes, Pat A. Wright, Louise Lemoine, Jane A. Bond, E. Dillwyn Williams, D. Wynford-Thomas

Journal:

Molecular Carcinogenesis

Year:

1992

Language:

english

File:

PDF, 1.23 MB

english, 1992

18

Direct growth stimulation of normal human epithelial cells by mutant p53

Fiona S. Wyllie, Nick R. Lemoine, Claire M. Barton, Tim Dawson, Jane Bond, David Wynford-Thomas

Journal:

Molecular Carcinogenesis

Year:

1993

Language:

english

File:

PDF, 559 KB

english, 1993

19

Toxicity of phorbol esters for human epithelial cells expressing a mutant ras Oncogene

Tim Dawson, Jane Bond, Neil Eccles, David Wynford-Thomas

Journal:

Molecular Carcinogenesis

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

20

Does telomere shortening drive selection for p53 mutation in human cancer?

Edward Bresnick, Nancy H. Colburn, Harold Moses, David Wynford-Thomas, Jane A. Bond, Fiona S. Wyllie, Christopher J. Jones

Journal:

Molecular Carcinogenesis

Year:

1995

Language:

english

File:

PDF, 545 KB

english, 1995

21

The polymerase chain reaction: Miracle or mirage? A critical review of its uses and limitations in diagnosis and research

Pat A. Wright, David Wynford-Thomas

Journal:

The Journal of Pathology

Year:

1990

Language:

english

File:

PDF, 1.72 MB

english, 1990

22

In situ hybridization—principles and practice. J. M. Polak and J. O'D. MCGEE (Eds). Oxford University Press, Oxford, 1990.1711620419. of pages: 247. price: £25. ISBN: 0 19 261906 3

D. Wynford-Thomas

Journal:

The Journal of Pathology

Year:

1990

Language:

english

File:

PDF, 124 KB

english, 1990

23

Oncogenes and anti-oncogenes; the molecular basis of tumour behaviour

D. Wynford-Thomas

Journal:

The Journal of Pathology

Year:

1991

Language:

english

File:

PDF, 1.39 MB

english, 1991

24

Medical perspectives series: Oncogenes and tumour suppressor genes. F. Mcdonald and C. H. J. Ford. BIOS Scientific Publishers, Oxford, 1991. No. of pages: 101. Price: £11.95. ISBN: 1 872 748 55 4

D. Wynford-Thomas

Journal:

The Journal of Pathology

Year:

1992

Language:

english

File:

PDF, 101 KB

english, 1992

25

P53 in tumour pathology: Can we trust immunocytochemistry?

David Wynford-Thomas

Journal:

The Journal of Pathology

Year:

1992

Language:

english

File:

PDF, 188 KB

english, 1992

26

Mutations in familial cancer

P. A. Wright, D. Wynford-Thomas

Journal:

The Journal of Pathology

Year:

1994

Language:

english

File:

PDF, 368 KB

english, 1994

27

Author's reply

D. Wynford-Thomas

Journal:

The Journal of Pathology

Year:

1995

Language:

english

File:

PDF, 138 KB

english, 1995

28

Telomerase activity and telomere length in thyroid neoplasia: biological and clinical implications

Paul Matthews, Christopher J. Jones, Julia Skinner, Michele Haughton, Catherine de Micco, David Wynford-Thomas

Journal:

The Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 203 KB

english, 2001

29

Immunohistochemical localization of cell surface receptors using a novel method permitting simple, rapid and reliable LM/EM correlation

David Wynford-Thomas, Bharat Jasani, Geoffrey R. Newman

Journal:

Journal of Molecular Histology

Year:

1986

Language:

english

File:

PDF, 3.14 MB

english, 1986

30

Detection of theH-RASoncogene in human thyroid anaplastic carcinomas

B. M. Stringer, J. M. Rowson, M. H. Parkar, J. M. Seid, P. R. Hearn, D. Wynford-Thomas, S. Ingemansson, N. Woodhouse, M. H. Goyns

Journal:

Cellular and Molecular Life Sciences

Year:

1989

Language:

english

File:

PDF, 1.60 MB

english, 1989

31

Control of growth in the rat thyroid-an example of specific desensitization to trophic hormone stimulation

D. Wynford-Thomas, B. M. J. Stringer, H. R. Harach, E. D. Williams

Journal:

Cellular and Molecular Life Sciences

Year:

1983

Language:

english

File:

PDF, 726 KB

english, 1983

32

Investigation of putative control mechanisms for thyroid growth

David Wynford-Thomas, Bradley Michael John Stringer, Hector Ruben Harach, Edward Dillwyn Williams

Journal:

Virchows Archiv B Cell Pathology Zell-pathologie

Year:

1982

Language:

english

File:

PDF, 403 KB

english, 1982

33

Segregational fidelity of chromosomes in human thyroid tumour cells

E. M. Parry, H. Ulucan, F. S. Wyllie, D. Wynford-Thomas, J. M. Parry

Journal:

Year:

1998

Language:

english

File:

PDF, 288 KB

english, 1998

34

Characterisation of novel mutations in Cockayne syndrome type A and xeroderma pigmentosum group C subjects

Andrew J. Ridley, James Colley, David Wynford-Thomas, Christopher J. Jones

Journal:

Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

35

How may clonality be assessed in human tumours?

G.T. WILLIAMS, D. WYNFORD-THOMAS

Journal:

Year:

1994

Language:

english

File:

PDF, 744 KB

english, 1994

36

10.1038/39207

Wynford-Thomas, David, Kipling, David

Journal:

Year:

1997

Language:

english

File:

PDF, 158 KB

english, 1997

37

10.1038/71630

Faragher, Richard G.A., Wyllie, Fiona S., Jones, Christopher J., Skinner, Julia W., Haughton, Michele F., Wallis, Corrin, Wynford-Thomas, David, Kipling, David

Journal:

Nature Genetics

Year:

2000

Language:

english

File:

PDF, 451 KB

english, 2000

38

Optimisation of conditions for detection of activated oncogenes by transfection of NIH 3T3 cells

Lemoine, NR, Wynford-Thomas, V, Wynford-Thomas, D

Journal:

British Journal of Cancer

Year:

1987

Language:

english

File:

PDF, 669 KB

english, 1987

39

Loss of dependence on IGF-1 for proliferation of human thyroid adenoma cells

Williams, DW, Williams, ED, Wynford-Thomas, D

Journal:

British Journal of Cancer

Year:

1988

Language:

english

File:

PDF, 879 KB

english, 1988

40

Ha-ras restriction fragment length polymorphisms in colorectal cancer

Wyllie, FS, Wynford-Thomas, V, Lemoine, NR, Williams, GT, Williams, ED, Wynford-Thomas, D

Journal:

British Journal of Cancer

Year:

1988

Language:

english

File:

PDF, 1.24 MB

english, 1988

41

Thyroid epithelial cell transformation by a retroviral vector expressing SV40 large T

Burns, JS, Lemoine, L, Lemoine, NR, Williams, ED, Wynford-Thomas, D

Journal:

British Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 1.62 MB

english, 1989

42

Structure and expression of nuclear oncogenes in multi-stage thyroid tumorigenesis

Wyllie, FS, Lemoine, NR, Williams, ED, Wynford-Thomas, D

Journal:

British Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 1.34 MB

english, 1989

43

Papillary and follicular thyroid carcinomas show a different pattern of ras oncogene mutation

Wright, PA, Lemoine, NR, Mayall, ES, Wyllie, FS, Hughes, D, Williams, ED, Wynford-Thomas, D

Journal:

British Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 430 KB

english, 1989

44

Characterisation of human thyroid epithelial cells immortalised in vitro by simian virus 40 DNA transfection

Lemoine, NR, Mayall, ES, Jones, T, Sheer, D, McDermid, S, Kendall-Taylor, P, Wynford-Thomas, D

Journal:

British Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 2.01 MB

english, 1989

45

Induction of cell death by stimulation of protein kinase C in human epithelial cells expressing a mutant ras oncogene: a potential therapeutic target

Hall-Jackson, CA, Jones, T, Eccles, NG, Dawson, TP, Bond, JA, Gescher, A, Wynford-Thomas, D

Journal:

British Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 3.30 MB

english, 1998

46

Extensive allelic variation and ultrashort telomeres in senescent human cells

Baird, Duncan M., Rowson, Jan, Wynford-Thomas, David, Kipling, David

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 190 KB

english, 2003

47

Human thyroid cancer cells as a source of iso-genic, iso-phenotypic cell lines with or without functional p53

Wyllie, F S, Haughton, M F, Rowson, J M, Wynford-Thomas, D

Journal:

British Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 483 KB

english, 1999

48

DNA damage checkpoint kinase Chk2 triggers replicative senescence

Wynford-Thomas, David, Brondello, Jean-Marc, Dulic, Vjekoslav, Gire, Véronique, Roux, Pierre

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 356 KB

english, 2004

49

Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells

Ivan, Mircea, Bond, Jane A, Prat, Maria, Comoglio, Paolo Maria, Wynford-Thomas, David

Journal:

Year:

1997

Language:

english

File:

PDF, 768 KB

english, 1997

50

Tolerance of high levels of wild-type p53 in transformed epithelial cells dependent on auto-regulation by mdm-2

Blaydes, Jeremy P, Gire, Véronique, Rowson, Janet M, Wynford-Thomas, David

Journal:

Year:

1997

Language:

english

File:

PDF, 679 KB

english, 1997